2004-06 IUPUI Campus Bulletin

Courses in Chemistry (CHEM)

Notes: P-prerequisite; C-corequisite; Fall-offered fall semester; Spring-offered spring semester; Summer-offered during one or both summer sessions; Day-offered as a daytime section; Night-offered as an evening section; Equiv.-course is equivalent to the indicated course taught at Indiana University Bloomington, the indicated course taught at the School of Science, IUPUI, or the indicated course taught at Purdue University, West Lafayette.

Undergraduate

C100 The World of Chemistry (3 cr.) P: None. Optional laboratory: C120. A topically oriented, non-mathematical introduction to the nature of matter. Topics covered include fossil fuel and nuclear sources of power; environmental issues involving chemistry such as recycling, acid rain, air and water pollution, global warming, ozone depletion; genetic modification of foods, DNA profiling, use of food additives and herbal supplements, and other public policy issues involving science.

C101 Elementary Chemistry I (3 cr., lecture, recitation) P: At least one semester of high school algebra. Usually taken concurrently with C121. Fall, day, night; Spring, day, night; Summer I, day. Essential principles of chemistry; atomic and molecular structure; bonding; properties and reactions of elements and compounds; stoichiometry; solutions; acids and bases. For students who are not planning careers in the sciences and for those with no previous course work in chemistry. Note: Most degree programs that include C101 require the concurrent laboratory, C121.

C102 Elementary Chemistry II (5 cr., lecture, recitation, laboratory; 3 cr., without laboratory) P: C101 (5 cr.). Equiv. PU CHEM 257-257L. Fall, even years, day; odd years, night; Spring, day, night; Summer II, day. Continuation of C101. Introduction to organic chemistry and biochemistry; organic compounds and their reactions.

C105 Principles of Chemistry I (3 cr., lecture, recitation) P: Two years of high school algebra, one year of high school chemistry. Equiv. PU CHEM 115, PU CHEM 125. Fall, day, night; Spring, day; Summer I, day. Usually taken concurrently with C125. A placement examination may be required for admission to this course. See text on page 42 under Chemistry Placement Examination. Principles of inorganic and physical chemistry emphasizing physical and chemical properties, atomic and molecular structure, chemical bonding and states of matter.

C106 Principles of Chemistry II (3 cr., lecture, recitation) P: C105 or equivalent. Equiv. PU CHEM 116, PU CHEM 126. Fall, day; Spring, day, night; Summer II, day. Continuation of C105. Usually taken concurrently with C126. Topics include condensed phases, solution chemistry, thermodynamics, equilibrium and kinetics.

C110 The Chemistry of Life (3 cr.) High school chemistry recommended. Equiv. IU C102, PU CHEM 257. Optional laboratory: C115. A non-mathematical introduction to organic molecules and their transformation to useful materials such as drugs and polymers. An emphasis is placed on the chemical features of biomolecules including hormones and neurotransmitters; proteins; lipids (fats); carbohydrates (sugars); and nucleic acids (DNA/RNA). The chemistry of enzymes, carcinogens, vitamins, antihistamines, anesthetics, genetic engineering, mental health, and other health-related topics.

C115 Laboratory for The Chemistry of Life (2 cr.) P or C: C110. Equiv. PU CHEM 257L. Laboratory work illustrating topics covered in C110.

C120 Laboratory for The World of Chemistry (2 cr.) P or C: C100. A hands-on approach to the topics discussed in C100.

C121 Elementary Chemistry Laboratory I (2 cr.) P or C: C101 (3 cr.) Fall, day, night; Spring, day, night; Summer I, day. Introduction to the techniques and reasoning of experimental chemistry. Emphasis is given to study of physical and chemical properties of inorganic compounds.

C125 Experimental Chemistry I (2 cr., lecture, laboratory) P or C: C105 or equivalent. Fall, day, night; Spring, day; Summer I, day. Laboratory work illustrating topics covered in C105.

C126 Experimental Chemistry II (2 cr., lecture, laboratory) P: C105 and C125; P or C: C106 or equivalent. Fall, day; Spring, day, night; Summer II, day. Continuation of C125. Laboratory work illustrating topics covered in C105 and C106.

C209 Special Problems (1-2 cr.) P: Two semesters of college chemistry and consent of instructor. Equiv. PU CHEM 290. Every semester, time arranged. Individually supervised special problems of chemical interest, e.g., environmental problems, development of experiments, development of audiovisual materials, etc. May be repeated for credit, but maximum of 2 credit hours may be applied toward a chemistry degree.

C301 Chemistry Seminar I (1 cr.) P or C: C409 and consent of instructor. Fall, day. Topics in various areas of chemistry. Students are required to attend departmental seminars and to prepare and present at least one seminar on their research. C301 and C302 may be elected three semesters for credit.

C302 Chemistry Seminar II (1 cr.) P or C: C409 and consent of instructor. Spring, day. Content same as C301.

C309 Cooperative Education in Chemistry (1 cr.) P: General and organic chemistry and consent of departmental chairperson. Every semester, time arranged. Industrial or similar experiences in chemically oriented employment. Grade is determined on basis of employment visitations, a written student report, and a supervisor evaluation report. May be repeated for a maximum of 5 credit hours of which 3 may be used to satisfy an advanced chemistry elective.

C310 Analytical Chemistry (3 cr.) P: C106. With C311, Equiv. PU CHEM 321. Fall. Fundamental analytical processes including solution equilibria, theory and applications of electrochemistry and spectrophotometry, and chemical methods of separation.

C311 Analytical Chemistry Laboratory (1 cr.) P or C: C310. Fall. Laboratory instruction in the fundamental analytical techniques discussed in C310.

C325 Introductory Instrumental Analysis (5 cr.) P: C310, C311. Spring. Instrumental methods of chemical analysis and separation for the chemical technician or preprofessional chemistry major.

C341 Organic Chemistry I (3 cr.) P: C106. Equiv. PU CHEM 261. Fall, day, night; Spring, even years, day; odd years, night; Summer I, day. Comprehensive study of organic compounds. Valence bond theory, stereochemistry, and physical properties of organic compounds are discussed in detail. Introduction to reaction mechanisms and to spectroscopic identification. Synthesis and reactions of selected compounds are also discussed.

C342 Organic Chemistry II (3 cr.) P: C341. Equiv. PU CHEM 262. Fall, even years day, odd years, night; Spring, day, night, Summer II, day. Continuation of CHEM 341. The chemistry of aromatic compounds and other major functional groups are discussed in detail. Multistep synthetic procedures and reaction mechanisms are emphasized. Introduction to biological chemistry.

C343 Organic Chemistry Laboratory I (2 cr.) P or C: 341. Equiv. PU CHEM 265. Fall, day, night; Spring, day, night; Summer I, day, night.Fundamental laboratory techniques of organic chemistry, introduction to spectroscopic methods of compound identification, and general synthetic methods.

C344 Organic Chemistry Laboratory II (2 cr.) P or C: 342; P:C343. Equiv. PU CHEM 266. Fall, night; Spring, day, night; Summer II, day, night. Preparation, isolation, and identification of organic compounds, spectroscopic methods of compound identification, qualitative organic analysis, multistep synthesis.

C360 Elementary Physical Chemistry (3 cr.) P: C106, MATH 222, PHYS P202. Spring, even years, day; Spring, odd years, night. Properties of gases and liquids, intermolecular forces, diffusion, chemical thermodynamics, ligand binding, kinetics, and introduction to quantum chemistry and spectroscopy. Includes topics in biophysical chemistry. For students who desire a survey course in physical chemistry.

C361 Physical Chemistry of Bulk Matter (4 cr.) P: C106, MATH 164, and PHYS P202 or PHYS 251 and C:MATH261. Equiv. PU CHEM 373 and 374. Spring, even years, day; Spring, odd years, night. Kinetic-molecular theory, gases, liquids, thermodynamics, statistical mechanics, solutions, transport properties, and phase and chemical equilibria.

C362 Physical Chemistry of Molecules (4 cr.) P: C106, MATH 164, and PHYS P202 or PHYS 251 and C:MATH261. Equiv. PU CHEM 375. Fall, odd years, day; Fall, even years, night. Quantum chemistry, symmetry, atomic and molecular structure and spectra, solids, chemical kinetics, photochemistry, and introduction to statistical thermodynamics.

C363 Experimental Physical Chemistry (2 cr.) P: C361 and C: C362 or P:362 and C:361. Equiv. PU CHEM 376. Fall, spring. Experimental work to illustrate principles of physical chemistry and to introduce research techniques.

C371 Chemical Informatics I (1cr.) P: C106, Fall.Basic concepts of information representation, storage, and retrieval as they pertain to chemistry. Structures, nomenclature, molecular formulas, coding techniques for visualization of chemical structures and properties.

C372 Chemical Informatics II (1cr.) P: C341 and C371, Spring. Basic concepts of information representation, storage, and retrieval as they pertain to chemistry with emphasis on "organic and biochemical knowledge." Spectral data representation and retrieval, crystallographic data systems, pattern recognition, instrumentation and laboratory networking, combinatorial chemistry, molecular modeling, and bioinformatics.

C409 Chemical Research (1-4 cr.) P: Junior or senior standing and consent of instructor. Equiv. PU CHEM 499. Every semester, time arranged. Chemical or literature research with a report. Can be elected only after consultation with research advisor and approval of program. May be taken for a total of 10 credit hours, which count toward graduation. Three credit hours may be used to satisfy the advanced technical elective in the Bachelor of Science in Chemistry degree program.

C410 Principles of Chemical Instrumentation (3 cr.) P: C310, C311, C361. P or C: C362. Equiv. PU CHEM 424. Fall. Modern methods of instrumental analysis, including spectroscopy, chromatography, and electrochemistry.

C411 Principles of Chemical Instrumentation Laboratory (2 cr.) P: C311. P or C: C410. Fall. Laboratory instruction in the instrumental analysis techniques discussed in C410.

C430 Inorganic Chemistry (3 cr.) P: C362. Equiv. PU CHEM 342. Spring. Atomic structure; periodic trends and properties of the elements. Introduction to symmetry and group theory. Valence bond, molecular orbital and ligand field theories of bonding and their application to structure and properties of inorganic and organometallic compounds. Spectroscopic properties and acid-base, oxidation-reduction, and coordination reactions of inorganic compounds.

C435 Inorganic Chemistry Laboratory (2 cr.) P or C: C430. Spring. Synthesis, characterization, and study of chemical and physical properties of inorganic and organometallic compounds.

C471 Chemical Information Sources (1cr.) P: C341, Fall.Techniques for the storage and retrieval in both printed and computer-readable formats; sources of chemical information, including Chemical Abstracts; development of search strategies; online searching of chemical databases.

C472 Computer Sources for Chemical Information (1cr.) P: C471, Spring. Techniques for the utilization of the major computer-based information tools found in academic and industrial environments.

C483 Biological Chemistry (3 cr.) P: C342, and one semester of physical chemistry or consent of instructor. Fall. The chemical and biophysical properties of biologically important molecules and systems. Special emphasis on the relationship between structure and function in proteins, nucleic acids, and biomembranes, as well as bioenergetics, kinetics, allosteric interactions, and enzyme catalysis.

C484 Biomolecules and Catabolism (3 cr.) P: C483. Spring. Mechanisms of biological catalysis, metabolism, biosynthesis, regulation of genetic information, and molecular biology.

C486 Biological Chemistry Laboratory (2 cr.) P: C483 or equivalent. Spring. An introduction to the important laboratory techniques currently employed by practicing biological chemists, including biomolecule isolation, purification, enzyme kinetics, and biomolecule characterization by electrophoresis, centrifugation, and spectroscopic methods.

C495 Capstone in Chemistry (1 cr.) P: Senior standing, B.A. or B.S. program. Fall, day; Spring, day. Independent study, under the supervision of a chemistry faculty member or appropriate academic advisor can be earned by completion of (a) a chemical research project; (b) a library research project in an area of current scientific investigation; (c) a research investigation in industry; or (d) a service activity in university, government, public schools, or other science-related groups or organizations. Students will report the results of their activities in both a formal written report and oral presentation, prepare portfolios of undergraduate work in chemistry, discuss recent scientific literature, and explore chemistry in society. Enrollment in the Capstone in Chemistry requires joint approval of the capstone instructor and the independent project advisor.

C496 Methods in Teaching Chemistry (1 cr.) P: CHEM C105. Fall; Spring. Designed for workshop leaders, this course is intended to offer continued support and training in group dynamics and learning theory. The larger goals for this course are to continue the development of leadership skills, to foster ongoing communication among workshop leaders, and to provide an environment for reviewing content knowledge.

Graduate

Please consult the IUPUI Class Schedule for a listing of graduate lecture courses offered each Fall or Spring semester.

533 Introductory Biochemistry (3 cr.) P: C342 or equivalent. A rigorous one-semester introduction to biochemistry.

542 Inorganic Chemistry (3 cr.) P: C362 or equivalent or consent of instructor. Atomic structure; periodic trends and properties of the elements. Introduction to symmetry and group theory. Valence bond, molecular orbital, and ligand field theories of bonding and their application to structure and properties of inorganic and organometallic compounds. Spectroscopic properties and acid-base, oxidation-reduction and coordination reactions of inorganic compounds. Advanced topics in main group or transition element chemistry.

575 Intermediate Physical Chemistry (3 cr.) P: C362 or equivalent. Quantum theory of atoms and molecules; theories of chemical bonding; molecular spectroscopy; methods for determining molecular structure; electrical and magnetic properties.

599 Special Assignments (1-4 cr.) P: Consent of instructor. Every semester including summer I and II, time arranged. Directed reading or special work not included in other courses.

621 Advanced Analytical Chemistry (3 cr.) P: C310, C410. Equiv. IU CHEM C510. A critical survey of recent developments in chemical and instrumental methods of analysis.

629 Chromatographic Methods of Analysis (3 cr.) P: C410 or equivalent or consent of instructor. Principles and practice of modern gas and liquid chromatography and capillary electrophoresis are developed from an integrated point of view. Emphasis is placed both on theory and on features useful for practical analytical separations.

634 Biochemistry: Structural Aspects (3 cr.) P: C310, C342, C361, and C362 or equivalent. Chemistry of materials of biochemical interest: carbohydrates, lipids, proteins, amino acids, nucleic acids, porphyrins, biochemistry of blood.

636 Biochemical Mechanisms (3 cr.) P: One year of physical chemistry and 651. The chemical basis of enzymatic catalysis with particular emphasis on catalytic interactions important in aqueous media.

641 Advanced Inorganic Chemistry (3 cr.) P: C430 or 542 or equivalent or consent of instructor. Applications of symmetry and group theory to structure, bonding and spectral properties of inorganic compounds. Advanced topics in main group and transition element chemistry including determination of structure from physical and spectroscopic properties, bonding in coordination, and organometallic compounds and inorganic reaction mechanisms.

651 Advanced Organic Chemistry (3 cr.) P: 342 or equivalent. Modern structural organic chemistry. Introduction to bonding theory, stereochemistry, and computational chemistry.

652 Synthetic Organic Chemistry (3 cr.) P: 651 or 657. An advanced treatment of methods for preparing major types of organic functionalities and bonds, stressing stereochemical and regiochemical control, and employing mechanistic organic chemistry for understanding choice of reagents and reactions conditions.

657 Reaction Mechanisms (3 cr.) P: 342 or equivalent or consent of instructor. Modern structural organic chemistry, introduction to physical organic chemistry, mechanisms of representative reactions, and methods used for understanding reactivity in organic transformations.

672 Quantum Chemistry (3 cr.) P: One year of physical chemistry. Equiv. IU CHEM C661. Basic principles of classical and quantum mechanics; approximation methods; atomic structure; spectroscopy; application of group theory; theory of molecular bonding.

675 Chemical Kinetics (2 or 3 cr.) P: One year of physical chemistry. Equiv. IU CHEM C673. Experimental and theoretical considerations of chemical reaction rates and mechanisms.

682 Statistical Thermodynamics (3 cr.) P: C362 or equivalent. Application of statistical mechanics to the description of imperfect gases, liquids, and solutions, to order-disorder phenomena in solids and surfaces; Monte Carlo techniques and molecular dynamics.

696 Special Topics in Chemistry (1-3 cr.) P: Bachelor of Science in Chemistry from an accredited institution or consent of instructor. Lectures on selected topics of current interest, as follows:

Analysis and Characterization of Synthetic Polymers A description of the principles and techniques of solution characterization and molecular weight methods, polymer spectroscopy, thermal analysis, and evaluation of mechanical properties.

Analytical Spectroscopy Survey of modern techniques, applications of spectroscopy and imaging in analytical chemistry.

Applied Computational Chemistry and Molecular Modeling Applied computational techniques that are widely used in the chemical and pharmaceutical industry, including computational chemistry, molecular modeling and computer-aided synthesis.

Bioanalytical Chemistry Modern techniques for the study of biological macromolecules, such as protein and peptides, carbohydrates, DNA, RNA, and lipids, including (1) spectroscopy (UV-Vis, Raman, NMR, mass spectrometry, and light scattering); (2) bioseparations (chromatography, electrophoresis, and microdialysis); (3) electrochemistry (sensors, electron transfer, and LCEC); (4) miscellaneous topics (amino acid analysis, sequencing, microcalorimetry, and immunochemistry).

Biochemistry-Dynamic Aspects Mechanisms of biological catalysis, metabolism, biosynthesis, regulation of genetic information, and molecular biology.

Bioelectrochemistry Principles of electrochemical measurements including potentiometry, amperometry and linear sweep and cyclic voltammetry and application to the study and utilization of biological molecules. Topics covered include redox transformations in biological systems, electron transfer between electrodes and biological molecules, and electrochemical sensors for detection and quantitation of biological analytes.

Bioinorganic Chemistry A study of the occurrence, properties, and mechanistic roles of transition and main group elements in biological processes including photosynthesis, oxygen evolution, respiration, nitrogen fixation, metabolic detoxification, and electron transfer.

Bioorganic Chemistry Structure and reactivity of biological macromolecules, such as proteins, enzymes, and nucleic acids, and their relevance to bioorganic chemistry. Current experimental studies of enzymes, nucleic acids, and model systems.

Biomaterials Introduction to the field of biomaterials science including chemistry, physics, and engineering of biomaterials; biological and biochemical aspects of biomaterials; and biomaterials in medicine.

Biophysical Chemistry The study of structure and properties of biologically important macromolecules in solution using physical techniques, with special emphasis on optical, fluorescence, and magnetic resonance spectroscopy to describe protein conformation, denaturation, catalytic center structure, thermodynamics of ligand binding, time dependent processes, and membrane properties.

Chemical Information Technology Overview of chemical informatics techniques, including chemical information and data systems, chemical structure and data representation and search systems, and bioinformatics techniques.

Electroanalytical Chemistry Principles of modern methods of electroanalytical chemistry and quantitative applications to electrode reaction mechanisms and analytical determinations.

Medicinal Chemistry The application of basic concepts of organic chemistry, biochemistry, and pharmacology to the design of organic medicinal agents as well as recent advances in synthesis and evaluation of pharmaceuticals.

Organometallics in Organic Synthesis Recent developments in the use of transition metals in synthetic organic methodology. Emphasis is placed on applications of methods in the synthesis of complex organic molecules.

Protein Structure and Function Physical forces stabilizing protein structure; protein folding. Essential features of macromolecular interactions. Introduction to enzyme kinetics and chemical mechanism in enzyme reactions.

Group Theory in Chemistry This course is on molecular symmetry and how we obtain information about the quantum states of molecules through application of group theoretical techniques related to the symmetries of molecules.

698 Research M.S. Thesis (cr. arr.)

699 Research Ph.D. Thesis (cr. arr.)