2004-06 IUPUI Campus Bulletin

Courses in Biology (BIOL)

All courses designed for the biology major are identified by the letter prefix K on the course number or have no prefix. All courses identified by the letter prefix N are primarily designed to serve students uncommitted to a degree in biology or students for whom these courses are appropriate to their curricular program (e.g., allied health).

Note: P-prerequisite; C-corequisite; Fall-offered fall semester; Spring-offered spring semester; Summer-offered during one or both of the summer sessions; Day-offered as a daytime section; Night-offered as an evening section; Equiv.-course is equivalent to the indicated course taught at Indiana University Bloomington, or the indicated course taught at Purdue University, West Lafayette.

Undergraduate Level

K101 Concepts of Biology I (5 cr.) P: High school or college chemistry. Fall, day; Spring, day, night; Summer, day. An introductory course emphasizing the principles of cellular biology; molecular biology; genetics; and plant anatomy, diversity, development, and physiology.

K103 Concepts of Biology II (5 cr.) P: K101. Fall, day, night; Spring, day; Summer, day. An introductory biology course emphasizing structure, physiology, development, diversity, and behavior in animals, and evolution and ecology of plants and animals.

K295 Special Assignments (arr.) P: Consent of instructor. Fall, Spring. Special work, such as directed readings, laboratory or field work, or presentation of material not available in the formal courses in the department.

K309 Computer Applications in Biology and Medicine (3 cr.) P: Sophomore standing and one semester of biology. Spring, day. Provides the undergraduate with experience in the major applications of the computer to the life sciences. Topics: computer hardware, software, BASIC programming concepts, and application packages. Projects: micro and mainframe computer experiences with databases, simulations, statistical packages, computer graphics, networks, and computer interfacing to laboratory equipment.

K322 Genetics (3 cr.) P: K103, CHEM C106. Fall. Spring of even-numbered years. Principles of genetics at the molecular, cellular, organismal, and population level.

K323 Genetics Laboratory (2 cr.) P or C: K322. Fall, day. Applied principles of genetics using organisms of increasing complexity, from viruses to the fruit fly.

K324 Cell Biology (3 cr.) P: K103, CHEM C106. Spring, day. Examination of the structure and activity of eukaryotic cells and subcellular structures. Emphasis is on regulation of and interactions among subcellular events such as protein targeting, transmembrane signaling, cell movement, and cell cycle.

K325 Cell Biology Laboratory (2 cr.) P or C: K324. Spring, day. Experiments on the molecular and biochemical basis of organization and function of eukaryotic cells.

K331 Embryology (3 cr.) P: K103. Fall, Spring, day. The development of animals through differentiation of cells, tissues, organs, and organ systems will be examined.

K332 Plant Growth and Development (3 cr.) P: K101, CHEM C341. Fall, day. An examination of growth and developmental patterns in plants as affected by growth regulators, age, heredity, photoperiod, and environmental factors.

K333 Embryology Laboratory (1 cr.) P or C: K331. Spring, day. Processes of animal development are examined in a series of classical and modern experiments using cell, tissue and embryo culture, drug treatments, and microscopic techniques.

K338 Introductory Immunology (3 cr.) P: K103, CHEM C106. Fall, day, night. Principles of basic immunology with an emphasis on the cells and molecules underlying immunological mechanisms.

K339 Immunology Laboratory (2 cr.) P or C: K338. Fall, day, night. Demonstration of immunological principles by experimentation. Exercises include cells and factors of the innate and the adaptive immune systems.

K341 Principles of Ecology (3 cr.) P: K103. Fall, day. A study of the basic concepts of the interrelation of living organisms and their environment.

K342 Ecology Laboratory (2 cr.) P or C: K341. Fall, day. Experiments in the laboratory and field to illustrate the principles and techniques of ecology.

K345 Behavioral Ecology (3 cr.) P: K341. Spring, night. An examination of the relationships among ecology, evolution, and behavior, including sexual selection and conflict, mating systems, altruism, and communication among animals.

K350 Comparative Animal Physiology (3 cr.) P: N107 or K103, CHEM C106. Spring, day. A comparative examination of principles of animal physiology from molecular to organismal levels using homeostasis, regulation, and adaptation as central themes.

K356 Microbiology (3 cr.) P: K103, CHEM C341. Spring, day, night. Introduction to microorganisms: cytology, nutrition, physiology, and genetics. Importance of microorganisms in applied fields including infectious disease.

K357 Microbiology Laboratory (2 cr.) P or C: K356. Spring, day. Laboratory experiments and demonstrations to yield proficiency in aseptic cultivation and utilization of microorganisms; experimental investigations of biological principles in relation to microorganisms.

K483 Biological Chemistry (3 cr.) P: CHEM C342. Fall, day. Chemistry of biologically important molecules including carbohydrates, lipids, proteins, and nucleic acids. Special emphasis on chemistry of intermediary metabolism.

K484 Cellular Biochemistry (3 cr.) P: CHEM C342. Spring, day, night. Emphasis on selected topics in cellular biochemistry including nucleic acid : protein interactions, protein : protein interactions, protein synthesis, biogenesis of membranes, and signal transduction. Current techniques for studying these processes in higher eukaryotes will be discussed.

K490 Capstone (1 cr.) P: Senior standing. Faculty-directed or approved independent library research on an area of public, scientific interest or a community service activity in local industry, government, schools, or other public science-related groups or organizations. Topics for independent research and a list of service opportunities are available in the Department of Biology Office.

K493 Independent Research (1-3 cr.) P: Consent of instructor. Fall, Spring, Summer. A course designed to give undergraduate students majoring in biology an opportunity to do research in fields in which they have a special interest.

K494 Senior Research Thesis (1 cr.) P: K493. Fall, Spring, Summer. A formally written report describing the results or accomplishments of K493.

Undergraduate and Graduate Level

507 Principles of Molecular Biology (3 cr.) P: K322, CHEM C342, or consent of instructor. Fall, night. Molecular aspects of structure and function of nucleic acids and proteins, including recombinant DNA research. Prokaryotic and eukaryotic molecular biology are given equal weight.

516 Molecular Biology of Cancer (3 cr.) P: CHEM C342 and K322 or a course in biochemistry. A detailed course examining the molecular mechanisms controlling the growth of animal cells. Emphasis on current experimental approaches to defining the molecular basis of growth regulation in developing systems and the uncontrolled proliferation of cells in metabolic disorders, such as cancer.

530 Introductory Virology (3 cr.) P: K356, CHEM C342. Fall, odd years, night. Detection, titration, and chemistry of viruses; viral host interactions: bacteriophage-bacterium, animal virus-animal cell, plant virus-plant cell; tumor viruses: infection and transformation.

532 Topics in Bacteriology (2 cr.) P: K356, CHEM C342. Fall, even years, night. Selected topics in bacterial physiology: cell division, chemotaxis, bacterial plasmids, sporulation, bacterial toxins, recombinant DNA.

540 Topics in Biotechnology (3 cr.) P: K322 and CHEM C341 or consent of instructor. Fall, night. Examines research techniques and applications for several technologies situated at currently recognized biological frontiers including recombinant DNA technology, hybridoma technology, protein engineering, agricultural research, and microbiological engineering.

548 Techniques in Biotechnology (3 cr.) P: K322, CHEM C342, or consent of instructor. Fall, day, night. Laboratory experience in techniques applicable to biotechnology: protein chemistry, molecular biology, and immunology.

550 Plant Molecular Biology (3 cr.) P: K322, C341, or consent of instructor. Fall, day, night. A comprehensive study of plant molecular biology and plant molecular genetics. Topics will include the structure and expression of plant nuclear, chloroplast, and mitochondrial genomes, and plant viruses.

556 Physiology I (3 cr.) P: K103, CHEM C342. Fall, night. Principles of physiology: nerve and muscle, temperature regulation, ion and water balance.

557 Physiology II (3 cr.) P: 556 or consent of instructor. Spring, night. A study of human cardiovascular, pulmonary, blood, and gastrointestinal systems. Higher neuronal functions and intersystem interactions will be discussed.

559 Endocrinology (3 cr.) P: 556 or equivalent, and CHEM C342. Fall. The study of hormone function. Consideration will be given to the role of hormones in growth, development, metabolism, homeostasis, and reproduction.

561 Immunology (3 cr.) P: K103, CHEM C341. Spring, night. Introduction to basic principles and experimentation in cellular and humoral immunology.

564 Molecular Genetics of Development. (3 cr.) P: K322 or similar or consent of instructor. R: BIOL 566. Spring, day, night. Examines how key regulatory genes and molecular signaling pathways regulate development in both lower eukaryotic organisms and mammalian organ systems, with emphasis on the function and evolution of signaling molecules and transcription factor superfamilies.

566 Developmental Biology (3 cr.) P: K322. Fall. Principles of development with emphasis on concepts and underlying mechanisms, including descriptive, physiological, and molecular approaches.

568 Regenerative Biology and Medicine (3 cr.) P: K324 or K331 or a biochemistry course. Spring. This course examines the mechanisms of natural regeneration (regenerative biology) and the application of these mechanisms to the development of therapies to restore tissues damaged by injury or disease (regenerative medicine).

570 Biological Membranes (3 cr.) P: CHEM C342, or consent of instructor. Spring, night. An examination of structure and function of biological membranes. Topics include lipid and protein composition and interactions, physiological properties of membranes, physiological methods of analysis, model membrane systems, and survey of specific biological membranes and their modes of action.

571 Developmental Neurobiology (3 cr.) P: consent of instructor. Fall, odd years, night. The major phases of nervous system development beginning with neurolation and neurogenesis and ending with the onset of physiological activity will be studied in a variety of animals, mainly avians and mammals (including man). Neural developmental disorders and behavioral ontogeny will also be considered.

595 Special Assignments (1-3 cr.) P: Consent of instructor. Fall, Spring, Summer. Special work, such as directed reading, independent study or research, supervised library, laboratory or field work, or presentation of material not available in the formal courses of the department.

Graduate Level

641 Microbial Genetics (2 cr.) P: K323, CHEM C342, and consent of instructor. Spring, odd years, night. Genetics of bacteria, bacterial viruses, and other microorganisms with emphasis on organization, replication, and function of the genetic material.

651 Cellular Immunology (3 cr.) P: 561. Spring, night. Study of cells, molecules, and mechanisms comprising the cellular immune system in normalcy and disease.

696 Seminar (1 cr.) (May be repeated for credit.) Fall, Spring. Each semester there are several separate offerings. They will likely be on the following topics: biochemistry, biology teaching, ecology and population biology, genetics, mechanisms of development, microbiology, neurobiology, and plant physiology. Oral presentations required.

697 Special Topics (1-3 cr.) (May be repeated for credit.) Fall, Spring. The frontiers of biology. Critical examination of developments in the various specialties represented by the members of the department. Currently, advanced work in the following and related fields can be offered: molecular genetics; structure and biosynthesis of biologically significant molecules; the nature of biological specificity and enzyme catalysis; the fine structure and chemistry of subcellular particles, cells, and tissues; microbial and plant metabolism; comparative biochemistry; genetics and physiology of viruses, bacteria, fungi, protozoa, helminths, and cells of higher forms of life; the genetics, structure, development, and physiology of plants and animals, including endocrinology and work physiology; excitable membranes; neurobiology, ecology, systematics, and evolution of microorganisms, plants and animals; host-parasite relationships including immunology; and the teaching of biology. The field in which work is offered will be indicated in the student's record.

698 Research M.S. Thesis (cr. arr.)

699 Research Ph.D. Thesis (cr. arr.)

Courses for the Nonmajor

N100 Contemporary Biology (3 cr.) P: None. Fall, day, night; Spring, day, night; Summer. Selected principles of biology with emphasis on issues and problems extending into everyday affairs of the student.

N107 Exploring the World of Animals (4 cr.) P: None. Equiv. PU BIOL 109. Fall, day, night; Spring, day, night; Summer, day. This course introduces students to animals and their native environments. It surveys individual ecosystems and highlights the interactions, features, and characteristics of the animals found there. Examples of discussion topics include unique features of animals, animal relationships, societies and populations, exotic species, and behavior, including mating, communication, feeding and foraging, and migration. Environmental issues including the effects of pollution on ecosystems are also discussed. Not equivalent to K103.

N200 The Biology of Women (3 cr.) P: None. Fall, day, night; Spring, day, night; Summer. This course examines the biological basis for bodily functions and changes that take place throughout the life of females.

N212 Human Biology (3 cr.) P: None. Equiv. PU BIOL 201. Fall, day. First course in a two-semester sequence in human biology with emphasis on anatomy and physiology, providing a solid foundation in body structure and function.

N213 Human Biology Laboratory (1 cr.) P or C: N212. Fall, day. Accompanying laboratory for N212.

N214 Human Biology (3 cr.) P: N212. Equiv. PU BIOL 202. Spring, day. Continuation of N212.

N215 Human Biology Laboratory (1 cr.) P or C: N214. Spring, day. Accompanying laboratory for N214.

N217 Human Physiology (5 cr.) P: None. Equiv. IU PHSL P215. Fall, day; Spring, day; Summer, day. Lectures and laboratory work related to cellular, musculoskeletal, neural, cardiovascular, gastrointestinal, renal, endocrine, and reproductive function in humans.

N222 Special Topics in Biology (1-3 cr.) P: None. A variable topics course dealing with current topics in biology. In a given semester, a topic such as disease, genetics, the environment, etc., will be dealt with as a separate course.

N251 Introduction to Microbiology (3 cr.) P: One semester general chemistry or one semester life science. Spring, night. The isolation, growth, structure, functioning, heredity, identification, classification, and ecology of microorganisms; their role in nature and significance to humans.

N261 Human Anatomy (5 cr.) P: None. Equiv. IU ANAT A215. Fall, day, night; Spring, day, night; Summer, day, night. Lecture and laboratory studies of the histology and gross morphology of the human form, utilizing a cell-tissue-organ system-body approach.

N322 Introductory Principles of Genetics (3 cr.) P: N107 or K101. Equiv. PU AGR 430. Spring, night. Basic principles of plant and animal genetics. Emphasis on transmission mechanisms as applied to individuals and populations. For students in health and agricultural sciences.

N400 Biological Skills for Teachers (3 cr.) P: Consent of instructor. Fall, night. Concepts and laboratory skills necessary to prepare teachers with diverse backgrounds to return to graduate academic biology courses are reviewed. Topics include general principles of biology, biochemistry, and biomathematics.